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India is an effective pill
Most stories about Einstein and his idiosyncrasies are,[link widoczny dla zalogowanych], I suspect, merely apocryphal. But that doesn't diminish their innate charm. You have perhaps heard about the story of the chauffeur who ferried Einstein on his innumerable lecture tours round the US when he spoke about the theory of relativity.
But of the numerous not too well known anecdotes,[link widoczny dla zalogowanych], there is a delightful one about his superstitious beliefs. Eventually, Einstein stepped out of his house accompanied by a university colleague and fellow scientist. On spotting a horse-shoe lying on the lawn, Einstein picked up,[link widoczny dla zalogowanych], turned to his house and nailed it on the front door frame. Seeing this,[link widoczny dla zalogowanych], his colleague exclaimed: Mr Einstein, you do not have confidence in this nonsense that a horse-shoe nailed to the door-frame brings luck towards the occupants of the house? Einstein is supposed to have replied, I don't know. If Einstein will be believed, it doesn't matter what you are (believer or agnostic), fortune is really a certainty. That pretty much was previously the situation with drugs.
They'd bring relief if the patient supported them or otherwise. Well, avoid the same level of success or, at any rate, not for all ailments. Still,[link widoczny dla zalogowanych], it was there. However, that is changing as our lifestyles produce newer complications to the health. You can, for example,[link widoczny dla zalogowanych], be struggling with hypertension as well as your doctor's prescription may work wonderful. I possibly could be suffering from exactly the same condition and the same medicine dispensed by the same doctor may not work for me. Could it be since you are a tall, handsome bloke,[link widoczny dla zalogowanych], married for an accomplished woman and, most importantly, have a wonderfully understanding boss?
While I, poor me,[link widoczny dla zalogowanych], am short and dark, a guy no woman want to be viewed with, and with the added misfortune to be stuck in a dead-end job? Or perhaps is there some other reason we do not know yet? The drug industry doesn't know.
Actually, for certain kinds of ailments for example transmissions the hit rate is quite impressive. When it comes to lifestyle-related ailments (diabetes, hypertension, etc.) the challenge facing the is higher by a manifold order.
Research scientists in drug companies get around the issue by formulating a rather different hypothesis. When the end result is really a net decrease in the ultimate risk (a ruptured vessel from heightened blood pressure level) in the group taking the medicine as opposed to the group exposed to a placebo, the argues the medical fraternity must be permitted to prescribe the new drug as it promotes overall public health in the society.
Obviously, when the new drug works on very few people that there isn't any significant difference in the incidence of a fatal risk between your two categories of patients, the new drug won't be cleared. There's obviously the absolute minimum number on whom the brand new medicine has to work in order that it results in a statistically significant positive outcome. The refers to this because the Required to Treat' or NNT.
Murkier environmentThe strategic environment has got murkier for MNC pharma companies recently. The industry now finds that the new molecules of drugs introduced by it work for dwindling people than continues to be the situation previously,[link widoczny dla zalogowanych].
You might argue that this ought to be perfectly acceptable as, after all, everyone knows there might be just one winner inside a lottery but that has not prevented millions one of the public from buying it. People struggling with asthma regularly make a pilgrimage to a hakim in Hyderabad to partake of the tiny fish he administers. If it really worked on each and everyone that consumed it, the nation should right now have been rid of the asthma scourge.
Life is not so feasible for pharma MNCs. You will find the adverse side-effects of litigation to contend with too. If your new blockbuster medicine works for fewer and fewer people there are potential side-effects to any or all those who consume it, then sooner or later the economics must turn adverse.
Research reports on the pharma industry present a grim picture. The share of revenue from new drugs is falling. The R expenditure is declining. The bulk of the cash is devoted to finding a cure for cancer and success in the combat cancer is proving elusive. Cheaper generic versions of potential off-patent medicine is snapping in the MNCs' heels.
The only thing that may excite the stock market in regards to a drug company stock is a big-ticket acquisition, and India will do the job perfectly. After all,[link widoczny dla zalogowanych], we now have more than our great amount of cholera, typhoid, dengue and malaria infections diseases that consumers seem to need treatment for as often as they obtain the urge to eat pizzas.
(This article was published on October 2, 2011)
Keywords: pharma MNCs, litigation problems, drug prices,
The only way Pharma can be made to focus on medicine is to create stock markets irrelevant. First stock markets have linked to social security, pension, indicator of GDP and economic health it becomes essential for political stability on the planet. Somewhere there has to be a delinkage so a pharma company doesn't become larger than it's meant to be. Individual countries can look after themselves with regulations so they don't become pawn within the system - do not let policies be manipulated by considerations apart from the health of citizens. Today if cheaper medicines treat ailments, tomorrow expensive medicines cannot put a country about the back foot as lifestyle changes avoiding those diseases cannot be made overnight.
Cholera - water borne - water treatment plants the answer - with security - or else cheap medicines typhoid - air borne - decongestion, remove malnutrition, clean food
dengue and malaria - hygeine and mosquito elimination NREGA and MNREGS or PMGSY can in fact do or policy should allow generic drugs to coexist with MNC's that takeover few companies rather than a blanket ban to allow them to have some advantage albeit short term within the stock exchange while the other bulk drug generic manufacturers persist preferentially. They may compete and one will bite the dust eventually but that gives time for alternatives -
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